解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Plaque-induced lesions can produce peri-implant bone loss with ultimate implant loss. Although the peri-implant tissues seem to be more resistant than the periodontal ones to plaque and calculus, they can produce a more extensive spread of the infection to the deeper tissues around implants. The case of a 45-year-old ...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)93116-u
更新日期:1995-08-01 00:00:00
abstract::The ultimate goal of implantation of biomaterials in the skeleton is to reach full integration of the non-living implant with the living bone. The biomaterial can be used much as a bone graft, resorbing or dissolving as bone growth occurs, and the end result is a new remoulded bone. Calcium pyrophosphate, Ca2P2O7, is ...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)99642-y
更新日期:1995-07-01 00:00:00
abstract::A glass of nominal composition (wt%) 17.25 MgO-52.75 3CaO.P2O5-30 SiO2 and a glass-ceramic obtained from it showed surface modifications when immersed in an acellular medium having a composition similar to that of human blood plasma. A (Ca, P)-rich layer, with an approximate Ca/P atomic ratio of 1.7, identified as hyd...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)94146-c
更新日期:1995-07-01 00:00:00
abstract::In an in vitro study, we have quantitatively evaluated the capability of seven different types of silicone to retain a Staphylococcus aureus strain, isolated from a surgical wound. All the silicone specimens were taken from prostheses already used in plastic or ophthalmological surgery. Two polymers were used as contr...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)99694-h
更新日期:1995-06-01 00:00:00
abstract::A rapid and simple in vitro method is described which measures the extent of unrecoiled solids compression when a complex biopolymer is subjected to a centrifugal force. This method, termed the compaction assay, was used to assess the response of purulent cystic fibrosis (CF) sputum samples to the addition of recombin...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)91129-m
更新日期:1995-05-01 00:00:00
abstract::Membranes, clinically used to improve bone regeneration according to the osteopromotion principle, have primarily been made of expanded polytetrafluoroethylene (Gore-Tex Membrane). Recently, different types of biodegradable membranes have become available. This investigation explored the osteopromotive potential of 10...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)93857-a
更新日期:1995-05-01 00:00:00
abstract::Polydispersed poly(L-lactic acid) (PLLA) membranes comprised of blends of monodispersed PLLA of weight average molecular weight of 82,500 and 7600 were fabricated to investigate the effect of polydispersity on degradation characteristics. The PLLA blends exhibited large spherulites of high molecular weight chains embe...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)98816-w
更新日期:1995-04-01 00:00:00
abstract::The hydrolytic degradation of aliphatic polyesters derived from lactic and glycolic acids (PLA/GA polymers) has been previously shown to proceed heterogeneously in the case of large size devices, the rate of degradation being greater inside than at the surface. A qualitative model based on diffusion-reaction phenomena...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)93258-f
更新日期:1995-03-01 00:00:00
abstract::Suture materials may interact with immune competent cells and thereby affect localized immunity. Macrophages are central to the inflammatory response and coordinate wound healing. They are also involved in the clearance of foreign material, bacteria and malignant cells. We studied the influence of soluble factors asso...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)93852-5
更新日期:1995-03-01 00:00:00
abstract::Bioceramic coatings, created by the high velocity oxy-fuel combustion spraying of hydroxyapatite (HA) powders onto commercially pure titanium, were characterized in order to determine whether this relatively new coating process can be successfully applied to bioceramic coatings of orthopaedic and dental implants. Four...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)92122-m
更新日期:1995-02-01 00:00:00
abstract::This study reports the effect of varying the thickness of a commercial zinc polycarboxylate dental cement on its adhesion in a metal-to-metal single lap joint. The thickness was controlled externally in a specially designed apparatus, rather than by the inclusion of isodimensional glass spheres, as has been done previ...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)98279-n
更新日期:1995-01-01 00:00:00
abstract::We have investigated the interface between bone and hydroxyapatite (HA) chronically implanted in man. By light microscopy, HA appeared to bind directly to bone without intervening fibrous tissue. By transmission electron microscopy, two patterns were noted: (1) HA either bound directly to bone; or (2) electron-dense m...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(95)91093-e
更新日期:1995-01-01 00:00:00
abstract::Different families of functionalized polymers with potential as biomaterials, or for biomaterial modification, have been investigated. In particular, degradation studies have been performed on poly(amidoamines), a family of polymers obtained by polyaddition of amines to bisacrylamides, and endowed with heparin-complex...
journal_title:Biomaterials
pub_type: 杂志文章,评审
doi:10.1016/0142-9612(94)90275-5
更新日期:1994-12-01 00:00:00
abstract::Thrombomodulin (TM) is a newly described endothelial cell associated protein that functions as a potent natural anticoagulant by converting thrombin from a procoagulant protease to an anticoagulant. In this study, the immobilization of hTM was investigated in detail using surface modified polymers. As the basis of imm...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90238-0
更新日期:1994-11-01 00:00:00
abstract::Combinations of an alkali-containing calcium phosphate-like rhenanite, sodium whitlockite or calcium potassium phosphate and a chloride-containing calcium phosphate-like spodiosite or chloroapatite with or without additions of other calcium phosphates like monocalcium phosphate monohydrate, dicalcium phosphate or dica...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90084-1
更新日期:1994-10-01 00:00:00
abstract::There is extensive experimental and surgical experience with the use of bone tissue to fill defects in the skeleton, to bridge non-union sites, and to pack defects in bone created from cyst curettage. DP-bioactive glass with a chemical composition of Na2O 8.4%, SiO2 39.6%, P2O5 12% and CaO 40% has been reported as an ...
journal_title:Biomaterials
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract::In this study, acrylamide-maleic acid hydrogels containing different amounts of maleic acid have been prepared by irradiating with gamma radiation. They have been used in experiments on bovine serum albumin (BSA) adsorption. Acrylamide-maleic acid hydrogel containing 60 mg of maleic acid and irradiated at 5.20 kGy has...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90117-1
更新日期:1994-09-01 00:00:00
abstract::A UV-hardening lacquer material based on polyurethane, used in Philips compact disc lens systems, was tested as suitable material for low-cost intraocular lenses (IOLs). A slightly changed composition (code number I-0.5A) came out as the best and was subsequently tested, with reference to poly(methyl methacrylate) (PM...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90030-2
更新日期:1994-08-01 00:00:00
abstract::Thrombomodulin (TM) is a newly described endothelial cell-associated protein that functions as a potent natural anticoagulant by converting thrombin from a procoagulant protease to an anticoagulant. In this study, focussing on the application of TM for biomedical materials, recombinant human TM (hTM) was immobilized o...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90041-8
更新日期:1994-08-01 00:00:00
abstract::The metabolic disposition and elimination process of the anhydride co-polymer poly[1,3-bis(p-carboxy-phenoxypropane):sebacic acid] 20:80 [P(CPP:Sa)20:80] implanted in the rat brain was studied. Two polymers were prepared, one with [14C]SA and unlabelled CPP, and the other co-polymer with [14C]CPP and unlabelled SA. Wi...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90166-x
更新日期:1994-07-01 00:00:00
abstract::A newly developed bone equivalent hydroxyapatite was derived from veterinary bone (VHAP). Sections of 1 cm of six rabbit mandibles were equally replaced by this VHAP graft. Radiological studies by X-ray were performed pre-operatively, immediately, and 1, 2 and 3 months post-operatively. The graft host-bone interface w...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90211-9
更新日期:1994-06-01 00:00:00
abstract::A series of segmented polydimethylsiloxane (PDMS) polyurea-urethanes was synthesized based on hexane diisocyanate modified polyether-PDMS soft segments. The hard segments consisted of 4,4'-methylene diphenylene diisocyanate, which was chain extended with 1,4-butanediol. The effect of chemical composition of the polyet...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90218-6
更新日期:1994-05-01 00:00:00
abstract::Since the pore size distribution of a material in contact with bone is decisive for its type of link with the tissue, many granules are commercially available as fillers and as bone reconstructing materials. We propose a new technological procedure. The optimum architectural design for obtaining the most suitable link...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90228-3
更新日期:1994-05-01 00:00:00
abstract::Co-polymeric hydrogels of collagen and poly(hydroxyethyl methacrylate) (pHEMA) were prepared using an ammonium persulphate-sodium metabisulphite redox initiation technique. Fluorescein isothiocyanate (FITC)-labelled bovine serum albumin (BSA) was entrapped into these hydrogels. These gels were modified differently by ...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90251-8
更新日期:1994-04-01 00:00:00
abstract::A simple and sensitive method for the quantitative determination of solid-supported primary and/or secondary amino groups using commercially available reagents is described. The solid supports are treated in an aqueous environment with either 2-iminothiolane (ITL) or sulpho-succinimidyl-3-(4-hydroxyphenyl)propionate (...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90054-x
更新日期:1994-03-01 00:00:00
abstract::Mucoadhesive properties of several polymers, such as sodium alginate, hydroxypropylmethyl cellulose, scleroglucan, xanthan gum, polyacrylic acid (Carbopol), and poly co-(methyl vinyl ether-maleic anhydride) (Gantrez), have been investigated by comparing a thermodynamical and a mechanical approach. Surface properties o...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90064-7
更新日期:1994-02-01 00:00:00
abstract::The suitability of polymeric biomaterials as surfaces for the attachment and growth of cells has often been investigated in cell culture. In this study the contribution that serum fibronectin (Fn) or vitronectin (Vn) make to the attachment and spreading of cells cultured from explanted human bone (bone-derived cells) ...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90070-1
更新日期:1994-02-01 00:00:00
abstract::Bone tissue is an anisotropic non-homogeneous composite material composed of inorganic, bone mineral fibres (hydroxyapatite) embedded in an organic matrix (type I collagen and non-collagenous proteins). Factors contributing to the overall mechanical behaviour include constituent volume fraction, mechanical properties,...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90263-1
更新日期:1994-01-01 00:00:00
abstract::The present study deals with the effect of the type and chemical character of incorporated polyester (polyether blocks) on the hydrolytic stability of different types of polyurethane medical adhesive dressings. Diffusion parameters of the investigated polyurethane adhesives, giving information concerning the chemical ...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(94)90198-8
更新日期:1994-01-01 00:00:00
abstract::Hyaluronan (HL), a naturally occurring glycosaminoglycan, has been chemically modified through the esterification of its carboxylic groups with different types of alcohol. The physico-chemical properties of these new biopolymers allow the preparation of many biomaterials which may be used in several medical applicatio...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(93)90160-4
更新日期:1993-12-01 00:00:00
abstract::Highly cross-linked aliphatic polyurethane networks have been prepared by the bulk step reaction of low molecular weight polyols and hexamethylenediisocyanate (HDI). These polyurethane networks are optically transparent, colourless and autoclavable amorphous glassy thermosets, which are suited for use in ophthalmic ap...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(93)90210-s
更新日期:1993-11-01 00:00:00
abstract::To enable the synthesis of hydrogels containing microporosity, a family of pore generating additives (porogens) were synthesized from poly(ethylene glycols) (PEGs) with different molecular weights using naphthyl acetic acid. The products formed were characterized by UV-vis, differential scanning calorimetry and soluti...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(93)90206-h
更新日期:1993-11-01 00:00:00
abstract::Periosteal derived bovine osteoblast-like cells migrated in culture onto an ionomeric cement. Cell cultures were maintained for 4 weeks and used to study the in vitro behaviour of cells on the ionomeric bone cement (IC). The cells produced bone matrix proteins (osteocalcin, bone sialoprotein II) and were osteoblast-li...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(93)90133-m
更新日期:1993-10-01 00:00:00
abstract::A bilayer artificial skin composed of a silicone sheet and a collagen sponge sheet was developed by us in 1986, modifying Yannas and Burke's technique. It was used in experimental animals and clinically, both with success; but the artificial skin was inconvenient for clinical use in terms of disinfection and preservat...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(93)90197-a
更新日期:1993-10-01 00:00:00
abstract::Two types of isoelastic endosseous dental implants were produced and their functionality was tested. One type consisted of a porous sintered TiTa30 alloy, the other had a special surface structure consisting of titanium wire loops. Their mechanical properties were optimized by the production parameter (sintering and d...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(93)90129-p
更新日期:1993-10-01 00:00:00
abstract::The effect of hirudin, a known inhibitor of thrombin, was evaluated for whole blood samples in terms of platelet deposition/adhesion to a non-biological test surface (tetrafluoroethylene-propylene copolymer), adenosine diphosphate (ADP) release and reduction in platelet count during laminar shear flow for a shear rate...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(93)90009-q
更新日期:1993-09-01 00:00:00
abstract::The interfacial membrane harvested from failed joint replacements contains particulate debris from the materials used for the implant. To define the tissue response to particulate titanium alloy and hydroxyapatite (HA) alone, 16 mature New Zealand white rabbits were divided into 2 groups of 8 rabbits. Using sterile te...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(93)90035-z
更新日期:1993-08-01 00:00:00
abstract::Polymethyl methacrylate (PMMA) films were treated by oxygen plasma discharge followed by acrylic acid (AA) grafting. The amount of carboxyl groups introduced by the grafting of AA on to the film surfaces was in the range 0.47-9.48 mumol/cm2, depending on the pressure of the plasma chamber during the discharge treatmen...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(93)90045-4
更新日期:1993-08-01 00:00:00
abstract::We analysed tissues harvested during 24 retrievals of hip joint prostheses, with one or both articular components made of alumina. We describe the morphology of wear particles, measure their size and analyse their chemical composition. We relate histopathological aspects to the parameters that characterize ceramic wea...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(93)90175-2
更新日期:1993-07-01 00:00:00
abstract::Severe wear of the ultra-high molecular weight polyethylene (UHMWPE) components of total joint replacements limits their long-term success. In previous studies, the infrared spectra obtained on retrieved UHMWPE components were interpreted as evidence that the UHMWPE oxidizes in vivo. In direct contrast, infrared spect...
journal_title:Biomaterials
pub_type: 杂志文章
doi:10.1016/0142-9612(93)90062-7
更新日期:1993-07-01 00:00:00